Technology

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Senior Research Associate/Scientist, Cell Line Development

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking an organized and motivated Research Associate/Scientist to drive the application of new cell engineering technology in our Cell Line Development Core. The successful candidate will work closely with project teams to design and generate engineered cell lines in support of preclinical programs.

What You Will Do:

  • Employ viral and non-viral approaches to engineer mammalian cell lines in support of preclinical CAR T programs
  • Perform activities associated with generating and maintaining a master and working cell bank inventory
  • Perform standard QC processes on cell lines, including but not limited to mycoplasma testing and target expression validation
  • Generate certificate of analysis and associated documentation for delivered cell lines
  • Register cell lines and maintain inventory in LIMS 
  • Work closely with scientists to coordinate complex experiments
  • Assist cross-functional activities for project teams, including hand-offs, data analysis and presenting at project meetings
  • Stay up to date with current literature related to the scope of ArsenalBio’s research focus
  • What You Will Bring:

  • Education:  BS or MS in Cell or Molecular Biology, Biological Sciences or a related field
  • Experience:  BS with 4+ years or MS with 2+ years relevant research experience in industry or academia
  • Excellent aseptic cell culture techniques required
  • Experience with FACS, multi-colour flow cytometry, and data analysis required
  • Proficiency at using data analysis tools such as FlowJo and GraphPad Prism
  • Familiarity with basic molecular skills including cloning, PCR and RT-PCR; and automation is a plus
  • Ability to quickly adapt and learn new skills for changing research priorities
  • Flexible mindset with the ability to think outside the box, creative approach to problem-solving
  • Demonstrated ability to work well in a highly collaborative team environment, coordinate tasks across multiple projects to meet deadlines
  • Willingness to accept other responsibilities outside of initial job description
  • Strong organizational skills, record keeping and interpersonal communication skills (verbal and written)
  • Preferred Skills:
  • Expertise with CRISPR gene editing and lentiviral transduction workflows and cell engineering
  • Experience in working with lentivirus production and transduction is desirable
  • Experience in cell therapy or gene therapy field
  • We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    “Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”


    Tarjei Mikkelsen, PhD

    Chief Technology Officer

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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