Technology

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Senior Research Associate - Cell Line Development

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.  Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking an organized and motivated Senior Research Associate to assist with ongoing projects in the Cell Line Generation group. The successful candidate will work closely with our lead scientists to design and generate engineered cell lines and  work closely with various teams within ArsenalBio, in a matrixed environment, to coordinate tasks and prioritize projects to meet deadlines. 

What You Will Do:

Employ viral and non-viral approaches to engineer mammalian cell lines in support of preclinical CAR T programs

Perform activities associated with generating and maintaining a master and working cell bank inventory

Perform standard QC processes on cell lines, including but not limited to mycoplasma testing and target expression validation

Generate certificate of analysis and associated documentation for delivered cell lines

Register cell lines and maintain inventory in LIMS Work closely with scientists to coordinate complex experiments

Assist cross-functional activities for project teams, including hand-offs, data analysis and presenting at project meetings

Stay up to date with current literature related to the scope of ArsenalBio’s research focus

What You Will Bring:

Bachelors or Masters in Cell Biology or Biological Sciences

2+ years of relevant research experience in cell biology and cell line engineering; industry experience is preferred

Excellent aseptic cell culture techniques required

Experience with FACS, multi-colour flow cytometry, panels design and data analysis required

Experience in working with lentivirus production and transduction is desirable

Proficiency at using data analysis tools such as FlowJo and GraphPad Prism

Familiarity with basic molecular skills including cloning, PCR and RT-PCR; and automation is a plus

Ability to quickly adapt and learn new skills for changing research priorities

Flexible mindset with the ability to think outside the box, creative approach to problem-solving

Demonstrated ability to work well in a highly collaborative team environment, coordinate tasks across multiple projects to meet deadlines

Willingness to accept other responsibilities outside of initial job description

Strong organizational skills, record keeping and interpersonal communication skills (verbal and written)

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

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“Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”


Tarjei Mikkelsen, PhD

Chief Technology Officer

Benefits

Best in Class Health & Wellness Plans

Flexible Office Hours

Paid Parental Leave

Healthy Kitchen Snacks

Daily Catered Lunches

Free Onsite Fitness Center

Unlimited Vacation Days

Generous compensation and equity packages

Commuter Benefits