Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Scientist/Sr. Scientist I, Molecular Biology

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.

We are seeking a motivated Scientist to lead construct design, DNA construction, and the development of new technologies & capabilities in ArsenalBio’s Molecular Biology team as a part of our efforts to develop and commercialize curative immune cell therapies.

What You Will Do:

  • Design DNA constructs and libraries encoding synthetic circuits and therapeutic modules for high-throughput functional screens
  • Provide expertise in cloning & broader molecular biology applications and strategies as functional point lead for product and program development 
  • Develop, operationalize, and optimize automation-enabled capabilities to scale DNA construction and characterization
  • Work with interdisciplinary teams to establish and test novel adoptive cell therapy approaches
  • Collaborate with program management to set milestones, deliverables, and timelines for active products and programs 
  • Mentor and lead team members within the group in areas of technical expertise
  • Maintain familiarity with the relevant current literature and its application to synthetic biology and genome engineering
  • Coordinate tasks across multiple projects, demonstrating prioritization and planning
  • Interpret and effectively execute experiments in line with project timelines and goals

  • What Will You Bring:

  • PhD in molecular biology or a related field, or Masters with 5+ years relevant experience in industry or academia, or Bachelors with 7+ years of relevant research experience in industry or academia
  • Experience in designing complex, multi-part vectors for gene expression, genetic reporter systems, and genome engineering applications
  • Experience in devising sound cloning strategies for complex DNA construction 
  • Experience developing and optimizing protocols for nucleic acid cloning, amplification, modification and analysis 
  • Experience optimizing and developing protocols for DNA assembly and library construction for applications such as synthetic biology, functional genomics and/or protein engineering
  • Experience with automation and HTP cloning workflows
  • Working knowledge of next-generation sequencing technologies and workflows
  • Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done 
  • Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results 
  • Growth mindset with eagerness to learn & adapt, ability to think outside the box, creative approach to problem solving, and comfort in working with ambiguous data in an open-ended, exploratory process

  • What We Will Offer You: 
    ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge. 

    We have a robust mentorship program, and comprehensive development tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as they are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

    ArsenalBio prioritizes the providing of a safe and healthy workplace that is consistent with COVID-19 public health guidance and legal requirements.  In order to protect our employees and visitors, we require all visitors (including candidates) and employees to present proof of being fully vaccinated against COVID-19 when coming onsite.

    We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity, and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.


    “Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”

    Tarjei Mikkelsen, PhD

    Chief Technology Officer


    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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