Technology

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Scientist - Bioengineering and Assay Development

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.  Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.


We are seeking an outstanding Assay Development Scientist to join the Technology Development team. The successful candidate is expected to work effectively in cross-functional teams to drive the implementation of advanced immunological assays that are robust and scalable.

What You Will Do

  • Work with the Discovery and Technology Development teams to define, build, and scale-up advanced immunological assays such as cell killing, cytokine release, cell migration, cell persistence, and transcriptional profiling
  • Drive the design and implementation of scalable platforms for both 2D and 3D tumor modeling for use within the context of immuno-oncology
  • Support adoption of lab automation by the Discovery and Development teams
  • Perform other related duties as assigned and based on company needs
  • What You Will Bring

  • REQUIRED
  • Ph.D. in immunology, cell biology, molecular biology, bioengineering, or a related discipline with 3+ years developing novel assays and assay platforms
  • Proven ability to perform high-quality experiments using automation
  • Experience with culturing of mammalian cells in 3D contexts
  • Experience with at least one of: ELISA or other protein quantitation methods; multidimensional flow cytometry; advanced imaging; or genetically encoded readouts
  • Working knowledge of experimental design (DOE methodology), bench execution, process optimization, and statistical analysis of biological assays
  • Excellent verbal and written communication skills, with the ability to work independently and in a multi-team environment, along with a can-do attitude to solve challenging problems in a fast-paced work environment

  • PREFERRED
  • Experience in drug screening, oncology, immunology, developmental biology, or similar applied fields
  • Strong understanding of complexities of the tumor microenvironment
  • Strong working knowledge of cellular screening technologies, assay development, molecular biology, high content imaging applications (especially confocal imaging), genomics, and NGS
  • Experience with single-cell technologies
  • Experience with large-scale data analytics: R or python, AWS, image processing

  • Plus
  • Experience in technology transfer, including process documentation, user training, performing IQ/OQ/PQ
  • Experience working with laboratory information management system and electronic lab notebook
  • We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

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    “Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”


    Tarjei Mikkelsen, PhD

    Chief Technology Officer

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits