Technology

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

NGS Scientist

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.  Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking an outstanding scientist to drive NGS sample preparation and analysis methods.  The ideal candidate will have a broad understanding of next-generation sequencing and its applications and a proven track-record of developing innovative NGS protocols for solving complex biological problems.  As a strong technical contributor, this role will collaborate with internal and external stakeholders to advance ArsenalBio research.

What You Will Do:

Advance NGS technology utilization and understanding across the company

Create NGS libraries from single cells, tissues, and isolated DNA/RNA to drive both product and platform development

Develop new NGS library preparation strategies for bulk and single-cell applications

Contribute NGS expertise and leadership to cross-disciplinary product/platform development teams

Work closely with computational biologists to interpret data generated by novel and optimized assay schemesWrite protocols, develop procedures, and maintain accurate records

What You Will Bring:

Ph.D. (preferred) or Masters in a relevant scientific discipline, with 6+ years of full-time, hands-on NGS experience in an academic or industrial setting

Deep understanding of NGS library preparation, the principles of sequencing technologies, and NGS data analysis

Significant experience in troubleshooting, method development, and optimization of molecular biology-based assays

Previous work with a variety of NGS sample preparation workflows and analysis

Experience in high-content screening, single-cell genomics, or functional genomics

Experience with a broad variety of molecular biology and analytical techniques including qPCR, RT-qPCR, ddPCR, molecular cloning, gene editing, primer design, and nucleic acid isolation and manipulation.

Experience operating liquid handling robots or other lab automation for high-throughput assays

Familiarity with cell culture, cell staining, fluorescence microscopy, flow cytometry, and cell sorting

Experience in computational analysis of next-generation sequencing data

Ability to plan and perform systematic workflow and reagent optimization and familiarity with formal design of experiment (DOE) approaches

Meticulous attention to detail and strong record-keeping skills

Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done

Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results 

Flexible mind with the ability to think outside the box, creative approach to problem-solving, and comfort in working with ambiguous data in an open-ended, exploratory processExcellent verbal and written communication skills

Demonstrated ability to perform as a team player




We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

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“Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”


Tarjei Mikkelsen, PhD

Chief Technology Officer

Benefits

Best in Class Health & Wellness Plans

Flexible Office Hours

Paid Parental Leave

Healthy Kitchen Snacks

Daily Catered Lunches

Free Onsite Fitness Center

Unlimited Vacation Days

Generous compensation and equity packages

Commuter Benefits