Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Director, Cell Engineering

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.  Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking a Director, Cell Engineering to lead evaluation, adaptation and development of novel technologies for efficient non-viral genome engineering in human immune cells. This role will interact closely with colleagues and cross-functional teams across the entire ArsenalBio R&D organization to ensure flexible and scalable access to precisely engineered immune cells for research use, while ensuring transferability of product leads to clinical manufacturing.

What You Will Do

  • Lead and mentor a team dedicated to development and application of a state-of-the-art cell engineering technology platform
  • Evaluate, adapt and develop reagents, methods and technologies for precise and efficient genome engineering in primary immune cells
  • Collaborate with automation-, process- and software engineers and to scale and optimize the operation of the cell engineering platform
  • Collaborate with cross-disciplinary teams to apply the cell engineering platform to discover and develop effective therapeutic products from early-stage through pre-clinical research stages
  • Collaborate with executive and business development teams to develop publication, commercialization and partnering strategies leveraging the ArsenalBio cell engineering platform

  • What You Will Bring

  • PhD in cellular or molecular immunology, bioengineering or a similar field, with 12+ years of relevant experience in industry or academia
  • Experience with the application of CRISPR-based genome engineering to human immune cells and/or other primary cell types
  • Experience with isolation, expansion and phenotypic characterization of human immune cells
  • Experience with characterizing complex cell populations using high-parameter cytometry, next-generation sequencing and other advanced analytical methods
  • Experience with relevant molecular biology and protein engineering methods
  • Working knowledge of laboratory automation, including liquid handlers and automated cell isolation instruments
  • Working knowledge of methods for high-throughput functional genomics and/or genetic screening in complex cell populations
  • Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done
  • Demonstrated ability to recruit, mentor and enable diverse technical teams
  • Demonstrated ability to work well in a highly collaborative team environment, coordinate tasks across multiple projects to meet deadlines
  • Strong written and oral communication skills
  • We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.


    Recommended Jobs

    “Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”

    Tarjei Mikkelsen, PhD

    Chief Technology Officer


    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits