Technology

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Automation Engineer

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking a talented automation engineer to join the Technology Development team. In this role you will be charged with the design, implementation and support of end-to-end automation to enable Arsenal’s success in developing effective cell therapies.

What You Will Do:

  • Participate in the design of efficient end-to-end automated solutions within the Technology Development team in support of a rapidly growing research and development organization
  • Document requirements and specifications of automated systems 
  • Design and provision integrated robotics systems and build innovative laboratory automation tools, instruments, and technologies
  • Evaluate hardware, software, and end-user workflows bringing new ideas for process improvements and engineering approaches that maximize short and long term fidelity and efficiency benefits
  • Engage with integration vendors and coordinate the build of robotic systems, their installation, and testing
  • Design and execute optimization experiments with the aim to scale and fully automate cell engineering and profiling processes on robotic platforms
  • Develop and deploy automated assay workflows for high throughput processing, including requirements gathering, scripting, testing, optimization, and testing
  • Assist in service support of integrated robotics systems and various lab equipment
  • Contribute to the building of a world-class team focusing on a wide array of technologies, including laboratory automation, assay design, drug screening campaign design, and project planning
  • Bring a can-do attitude to solve new and challenging problems in a high pace environment
  • Perform other related duties as assigned and based on company needs
  • What You Will Bring

  • B.S. in biology, biochemistry, chemical engineering, applied physics, or closely related discipline
  • 3+ years developing and implementing high-efficiency workflows and automated systems for cell and molecular biology, ideally on end-to-end integrated robotic systems
  • Experience in the successful transfer of technologies from manual workflows into high-throughput systems
  • Experience scripting methods on OEM robotic systems (liquid handlers, imagers, scheduling software, etc.)
  • Strong computer skills and experience in one or more programming languages (e.g. VB/VBA/VBS, Python, C++/C#, .Net)
  • Experience with software engineering best practices: code quality, testing, performance optimization, development of research tools infrastructure
  • Good engineering techniques and best practices (i.e. design control, FMEA, risk analysis, stress testing)
  • Working with vendors, including building and maintaining relations
  • Excellent verbal and written communication skills with the ability to work independently and in a multi-team environment

  • Desired Skills and Background:
  • Experience in drug screening, oncology, immunology, developmental biology, or similar applied fields
  • Strong working knowledge of cellular screening technologies, assay development, molecular biology, and NGS
  • Working with complex integrated robotic systems, robotic arms/plate handlers, and automation workflow scheduling software
  • Working knowledge of experimental design (DOE methodology), bench execution, process optimization, and data analysis
  • Working knowledge of high throughput screening, high content imaging applications, NGS data analysis 
  • Experience with nucleic acid processing: whole genome, RNA, targeted enrichment and single-cell technologis
  • Experience working with a broad set of instruments and data: sequencers, plate readers, imagers, flow cytometers, FACS, qPCR, etc.
  • Experience in technology transfer, including process documentation, user training, performing IQ/OQ/PQ
  • Working with laboratory information management system and electronic lab notebook
  • Working in a regulated environment (CLIA / CAP / NYS / FDA / GCLP) and quality management systems
  • We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    “Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”


    Tarjei Mikkelsen, PhD

    Chief Technology Officer

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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