Technology

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

Accelerating and scaling immune cell engineering

Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

Automation Engineer

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking a talented automation engineer to join the Technology Development team. In this role you will be charged with the design, implementation and support of end-to-end automation to enable Arsenal’s success in developing effective cell therapies.

What You Will Do:

Participate in the design of efficient end-to-end automated solutions within the Technology Development team in support of a rapidly growing research and development organization

Document requirements and specifications of automated systems

Design and provision integrated robotics systems and build innovative laboratory automation tools, instruments, and technologies

Evaluate hardware, software, and end-user workflows bringing new ideas for process improvements and engineering approaches that maximize short and long term fidelity and efficiency benefits

Engage with integration vendors and coordinate the build of robotic systems, their installation, and testing

Design and execute optimization experiments with the aim to scale and fully automate cell engineering and profiling processes on robotic platforms

Develop and deploy automated assay workflows for high throughput processing, including requirements gathering, scripting, testing, optimization, and testing

Assist in service support of integrated robotics systems and various lab equipment

Contribute to the building of a world-class team focusing on a wide array of technologies, including laboratory automation, assay design, drug screening campaign design, and project planning

Bring a can-do attitude to solve new and challenging problems in a high pace environment

Perform other related duties as assigned and based on company needs

What You Will Bring

B.S. in biology, biochemistry, chemical engineering, applied physics, or closely related discipline

3+ years developing and implementing high-efficiency workflows and automated systems for cell and molecular biology, ideally on end-to-end integrated robotic systems

Experience in the successful transfer of technologies from manual workflows into high-throughput systems

Experience scripting methods on OEM robotic systems (liquid handlers, imagers, scheduling software, etc.)

Strong computer skills and experience in one or more programming languages (e.g. VB/VBA/VBS, Python, C++/C#, .Net)

Experience with software engineering best practices: code quality, testing, performance optimization, development of research tools infrastructure

Good engineering techniques and best practices (i.e. design control, FMEA, risk analysis, stress testing)

Working with vendors, including building and maintaining relations

Excellent verbal and written communication skills with the ability to work independently and in a multi-team environment

Desired Skills and Background:

Experience in drug screening, oncology, immunology, developmental biology, or similar applied fields

Strong working knowledge of cellular screening technologies, assay development, molecular biology, and NGS

Working with complex integrated robotic systems, robotic arms/plate handlers, and automation workflow scheduling software

Working knowledge of experimental design (DOE methodology), bench execution, process optimization, and data analysis

Working knowledge of high throughput screening, high content imaging applications, NGS data analysis

Experience with nucleic acid processing: whole genome, RNA, targeted enrichment and single-cell technologis

Experience working with a broad set of instruments and data: sequencers, plate readers, imagers, flow cytometers, FACS, qPCR, etc.

Experience in technology transfer, including process documentation, user training, performing IQ/OQ/PQ

Working with laboratory information management system and electronic lab notebook

Working in a regulated environment (CLIA / CAP / NYS / FDA / GCLP) and quality management systems

We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

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“Modern data science, automation, and synthetic biology approaches have tremendous potential to accelerate the development of effective cell therapies. ArsenalBio is being built from the ground up to optimize the leveraging of these approaches through early and deep integration of engineers and technologists into our R&D programs. We are seeking ambitious and talented teammates to join us in our mission to improve the lives of cancer patients.”

Tarjei Mikkelsen, PhD

Chief Technology Officer