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Director, NGS & Molecular Assays

Director, NGS & Molecular Assays

ArsenalBio, a privately held, clinical-stage programmable cell therapy company engineering advanced CAR T therapies for solid tumors, is seeking a talented Director, NGS & Molecular Assays to work onsite based in our South San Francisco office. 

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. With our programmable and computationally driven approach, our team is engineering living medicines to attack cancer’s inherent multi-faceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across immunology, synthetic biology, molecular biology, automation and computational biology, we are united in purpose to deliver radical breakthroughs for people with cancer, and prioritize the team’s outcomes over individual goals to achieve our company mission – together. 

The Director of NGS & Molecular Assays is responsible for leading NGS and molecular assays efforts to support R&D activities at ArsenalBio. This role is responsible for the pipeline of both routine and novel NGS methods and molecular assays. This individual will report to the VP of Technology and will work closely with other R&D teams, QA, Process Sciences, Technical Operations, and preclinical and clinical translational groups to bring new cell therapy products to market.

What You Will Do:

  • Lead R&D team effectively to produce a pipeline of both NGS and molecular assays
  • Develop assays to support discovery biology and IND-enabling research activities
  • Provide guidance and technical expertise to all ArsenalBio teams
  • Support product development and regulatory filings for pivotal clinical studies
  • Manage the completion of project deliverables and maintain timelines
  • Manage internal resource allocation and external collaborations
  • Prepare and review sections of INDs, abstracts, manuscripts, presentations, and technical reports
  • Contribute to scientific and strategy discussions to advance and enhance ArsenalBio’s platform and product candidates
  • Manage CROs to implement NGS and molecular biomarker assays to progress ArsenalBio’s programs efficiently to the clinic
  • Manage NGS operations, resources, and budgets

    • What Will You Bring:

  • Ph.D. in a Life Science field with experience in NGS and molecular assay technology development with 9+ years of relevant work experience and 7+ years of management experience preferred. MA/MS: Industry experience 14+ years required, BS/BA: Industry experience 16+ years required
  • Proven track record of managing high-performing teams of scientists and research associates
  • Strong leadership skills and a demonstrated ability to build and retain an effective team as a proven mentor, coach, motivator, and manager
  • Demonstrated ability to work collaboratively in a cross-functional matrixed environment
  • Deep understanding and experience with NGS platforms
  • Significant direct experience with single-cell sequencing, including 10x Genomics and SPLiT-seq approaches
  • Must have excellent troubleshooting, organization, planning skills, and the ability to work under timelines in a fast-paced environment
  • Demonstrated ability to effectively influence senior executives, and the capacity to develop, communicate, advocate for, and execute a scientific strategy
  • Excellent interpersonal, verbal, and written communication skills
  • Ability to credibly represent the company to external constituents, including KOLs, investors, and regulators
  • An outstanding work ethic coupled with an engaging disposition and strong entrepreneurial drive

    • What We Will Offer You: 
    An opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM to advance therapies to patients who need it most.

    ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge. 

    We have a robust mentorship program, and comprehensive development tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as they are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

    We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.
    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    The estimated base salary offer for the preferred primary location of San Francisco Bay area ranges from $194,300- 238,000. Salary ranges for other locations may vary from this range.   Base pay offered may vary depending on job related knowledge, experience, education, and location.  In addition to these factors, we believe in the importance of pay equity and consider internal equity of our current employees as part of any final offer.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    Accelerating and scaling immune cell engineering.

    Effective application of innovative technology in biological research requires a collaborative and cross-disciplinary mindset.

    We are a diverse group of engineers, scientists, and synthetic biologists dedicated to empowering our Discovery and Development organizations through design and deployment of state-of-the-art computational and biological tools.

    Benefits

    ArsenalBio is powered by people.

    And we believe that people work best when given freedom and flexibility in a supportive environment that allows us all to show up as our true selves. We respect that your life extends beyond the work we’ll do here together, and we continually strive to provide you with what you need to care for yourself and your family.

    Health & Wellness

    We offer comprehensive plans that cover medical, dental, vision, and wellness needs, paid at 100% for employees and 80% for eligible dependents. We also encourage and enable our team to enjoy an active lifestyle so we offer standing desks, daily catered lunches, unlimited healthy snacks, and an employer-funded Lifestyle Spending Account that can be used for fitness and wellness expenses. We also provide access to Spring Health, a platform designed to provide easy access to coaching and therapy services to support your mental well-being.

    Financial Well-Being

    We recognize that financial stability fosters peace of mind for our team and their families. We offer a 401(k) employer match, health savings account employer contributions, flexible spending accounts and company-paid life and AD&D insurance in addition to our generous compensation packages. Our team also enjoys free parking, pre-tax commuter benefits for using mass transit and parking, and monthly cell phone reimbursement.

    Time Off

    We want you to enjoy life. We prioritize work-life integration and offer a flexible time off policy, paid holidays and company shutdowns, flexible office hours, a paid leave program, and the permission to manage your time in a way that allows you to meet both your personal and professional responsibilities.

    Mindful Workspace

    Our new offices were thoughtfully designed with the humans of ArsenalBio in mind. With ergonomically-friendly furniture, an open workspace and state-of-the-art lab with inspiring views, collaborative break-out spaces, wellness rooms, micro-kitchens stocked with healthy snacks, and more, our office reflects our holistic commitment to health and happiness.

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.