Technical Operations

Senior Scientist, Analytical Development (Flow Cytometry)

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking a talented and motivated Senior Scientist to join the ArsenalBio Technical Operations team.  The individual will work closely with team members to develop flow cytometry based analytical test methods in support of characterization, release and stability testing of our cell therapy products. The individual will also interact cross-functionally across the organization to enable the success of ArsenalBio.

What You Will Do:

  • Independently design, test, and implement quality-based analytic assays to support the characterization and release of cell therapy products.
  • Actively contribute to development and efficient execution of muti-color flow cytometry assays for characterization of CAR T manufacturing process and drug products.
  • Provide analytical support for clinical-scale IND-enabling manufacturing operations, including assay qualification and assist in tech transfer in support of GMP lot release.
  • Provide technical expertise and leadership within project teams and in a matrix environment.
  • Establish tracking and trending analyses of process development and cGMP production runs, including evaluation of critical reagents and lot to lot variability, in order to improve process standardization.
  • Good understanding of cGMP environment, and Quality by Design (QBD) principles for process and assay development, qualification and validation preferred.
  • Collaborate closely with other functions to enable effective and successful project development; actively engage in cross-functional collaboration with peers to overcome challenges
  • Organize, communicate, and present complex data sets to key stakeholders and senior management
  • What You Will Bring:

  • PhD (preferred), Masters or Bachelors in a relevant scientific discipline (such as Biotechnology, Bioprocess engineering, Immunology, Molecular Biology, Biochemistry)
  • Years of relevant experience in academia or industry, and successful performance track record in establishing and applying analytical assays for cell therapy products as stated: PhD with minimum of 2 years, Masters with minimum 6+ years of industry experience, and Bachelors with minimum 8+ years of industry experience
  • 2+ years of hands-on experience of multi-color (10+) flow cytometry experience is a must.
  • Experience in cell therapy product development is a plus.
  • Proficiency in multi-dimensional data analysis and interpretation using software such as FlowJo and JMP.
  • Experience in technical development of analytic assays to support cell and gene therapy biologics and other advanced modalities in an early development setting 
  • Strong leadership skills and strategic problem-solving ability; ability to predict issues and identify solutions
  • Ability to lead successfully within extended project teams and handle multiple challenges under pressure
  • Excellent communications and presentation skills, written and verbal
  • Excellent organizational skills: Proactive, management of multiple tasks of varying complexity simultaneously
  • We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.


    Ken Drazan, MD
    Founding CEO

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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