Technical Operations

Scientist/Sr. Scientist, Gene Editing/Cell Isolation (2127-N-680-PDAD)

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking a talented and motivated scientist to join the ArsenalBio Technical Operations team. The individual will develop automated manufacturing processes (cell isolation, gene editing) and procedures that enable downstream work at ArsenalBio. Additionally, the individual will support evaluation and optimization of GMP-compatible processes and procedures that will lead to the effective manufacture of our cell therapy products. This position will manage 2+ direct reports. The individual will also interact cross-functionally within Process Development, Analytical Development, and across the organization to enable the success of ArsenalBio.

What You Will Do:

  • Plan, execute, analyze, and report on experiments and analytic assays to support the development of a GMP-compatible process to produce and characterize T cell therapy products
  • Manage a team of Research Associates and facilitate their projects/goals
  • Support evaluation and optimization of GMP-compatible processes and procedures 
  • Collaborate closely with other functions to enable effective and successful project execution
  • Actively engage in cross-functional collaboration with peers to overcome technical challenges
  • Organize, communicate, and present complex data sets to key stakeholders and senior management
  • Support cross-functional activities including hand-offs to various teams, compiling data, and presenting at project meetings
  • What You Will Bring:

  • Masters or PhD in a relevant scientific discipline (such as Biotechnology, Bioprocess engineering, Immunology, Molecular Biology, or Biochemistry)
  • Masters with 6+ years and PhD with 2 years of relevant research experience in T cell biology and/or immunotherapy preferred 
  • Expertise in human immune cell isolation, T cell expansion, T cell engineering (non-viral gene editing), and mammalian cell culture techniques required
  • Prior experience in cell therapy and/or process development teams preferred
  • Expertise in multi-color flow cytometry analyses including panel design and data analysis required
  • Understanding of cGMP environment, Design of Experiment (DOE), and Quality by Design (QBD) principles for process and assay development, qualification, and validation preferred. 
  • Experience in T cell functional assays including cytotoxicity, cytokine/chemokine, and proliferation a plus 
  • Ability to quickly adapt and learn new skills for changing research priorities
  • Flexible mind with the ability to think outside the box, creative approach to problem-solving
  • Demonstrated ability to work well in a highly collaborative team environment, coordinate and organize tasks across multiple projects to meet deadlines
  • Willingness to accept other responsibilities outside of initial job description
  • We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.


    Ken Drazan, MD
    Founding CEO

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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