Medical Sciences

Scientist I/Senior Scientist I, Preclinical Development (2232-N-615-MED)

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking a highly motivated and organized Scientist/Senior Scientist I to join our Preclinical  Development team. The successful candidate will contribute to the preclinical development of novel adoptive cell therapy products for solid tumors by planning, executing, analyzing, and reporting in vitro experiments, as well as supporting in vivo studies. ​​He/she will be expected to both work independently and also collaborate closely with various teams within ArsenalBio to coordinate tasks and execute projects to meet deadlines.


What You Will Do:

  • Independently plan, execute, analyze, and report on experiments to support the preclinical development of novel T cell therapy products across multiple pipeline programs
  • Perform in vitro cell-based functional assays (cytotoxicity, cytokine, proliferation, etc.) for CAR T cell therapeutic candidate selection
  • Design, execute, and analyze flow cytometry experiments for CAR T cell product characterization
  • Support engineered T cell production activities (e.x. gene editing, T cell culture, cryopreservation, cell thawing) 
  • Culture both engineered primary T cell and suspension/adherent cell lines
  • Support IND-enabling preclinical studies
  • Collaborate effectively on cross-functional activities for project teams, including hand-offs, data analysis, and presenting at project meetings
  • Maintain an up-to-date and detailed electronic lab notebook 
  • Organize, communicate, and present complex data sets to key stakeholders and senior management 
  • Coordinate tasks across multiple projects and teams, demonstrating prioritization and planning
  • Execute and interpret experiments effectively in line with project timelines and goals

  • What Will You Bring:

  • For Scientist I level: PhD in Cell or Molecular Biology, Biological Sciences or a related field OR Masters in Cell or Molecular Biology, Biological Sciences or a related field with 5+ years industry experience OR Bachelors in a related field with 7+ years industry experience; knowledge of CAR T cell therapy is a plus; industry experience is preferred
  • For Senior Scientist I level: PhD in Cell or Molecular Biology, Biological Sciences or a related field with 2+ years industry experience OR Masters in Cell or Molecular Biology, Biological Sciences or a related field with 7+ years industry experience OR Bachelors in a related field with 9+ years industry experience; knowledge of CAR T cell therapy is a plus; industry experience is preferred
  • Excellent mammalian cell culture skills are required
  • Experience with multi-colour flow cytometry, panel design, and data analysis is required, and expertise in this area is highly preferred
  • Experience with immunological assays, such as cytokine/chemokine analysis (e.x. ELISA or Luminex) and cytotoxicity, is highly preferred
  • Proficiency using data analysis tools such as FlowJo and GraphPad Prism is highly preferred
  • Experience mentoring/supervising junior research technicians is preferred
  • Ability to quickly adapt and learn new skills for changing research priorities
  • Demonstrated ability to work as a team player in a collaborative environment and coordinate tasks across multiple projects to meet deadlines
  • Strong organizational skills, record keeping, and interpersonal communication skills (verbal and written)
  • Flexible mind with the ability to think outside the box, creative approach to problem-solving
  • Willingness to accept responsibilities outside of initial job description
  • Passion for your work
  • A positive attitude

  • Preferred Skills:

  • Experience with primary T cell culture
  • Experience with CRISPR gene editing and cell engineering workflows 
  • Experience with Incucyte live cell imager
  • Experience with semi-automated pipetting workflows (e.x. Integra VIAFLO)


  • ArsenalBio prioritizes the providing of a safe and healthy workplace that is consistent with COVID-19 public health guidance and legal requirements.  In order to protect our employees and visitors, we require all visitors (including candidates) and employees to present proof of being fully vaccinated against COVID-19 when coming onsite.

    We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity, and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.


    Ken Drazan, MD
    Founding CEO

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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