Discovery

Bold ideas. Reliable data. World-Class Science.

Designing therapies to cure our most important health challenges requires the audacity to advance a bold idea and explore new biologies with world-class science.

By pushing at the frontiers of science, challenging what we think we know, and holding ourselves to the highest standards of irrefutable proof, we are reshaping the future of curative cellular therapies.

Senior/Staff Scientist - Discovery Oncology

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.  Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

ArsenalBio is seeking a Senior/Staff Scientist to lead our oncology target discovery as a part of our efforts to develop and commercialize curative immune cell therapies. This candidate will be primarily responsible for identification, prioritization, and early validation of targetable moieties using RNA and protein-based approaches.

What You Will Do

  • Lead efforts to identify target antigens for oncology CAR T applications
  • Identify in silico resources for target elucidation and de-risking  
  • Develop RNA- and protein-based platforms to validate lead target expression profiles 
  • Identify and develop reagents to enable target validation
  • Coordinate cell line engineering activities to confirm cell surface expression and enable screening platform development
  • Maintain familiarity with the relevant current literature and its application to binder discovery, screening methodologies, synthetic biology and cell therapy
  • Coordinate tasks across multiple projects, demonstrating prioritization and planning
  • Interpret and effectively execute experiments in line with project timelines and goals
  • Recruit and mentor junior scientists and research associates with relevant expertise
  • What You Will Bring

  • PhD in cancer, molecular or cellular biology or a related field, with 5+ years of relevant research experience in industry or academia
  • Experience with RNA and/or protein-based cell surface target discovery and validation approaches
  • Experience with mass-spectroscopy based discovery and validation approaches
  • Experience with protein-based abundance assessments including ELISA, flow cytometry, luminex, MSD, IHC, and western blotting
  • Experience supervising junior research technicians and scientists
  • Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done
  • Demonstrated ability to perform as a team player
  • We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.



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    “Curing patients is our goal. Success necessitates innovation and an open mind to explore the etiology of human disease and challenge and extend current paradigms of treatment. Diseases such as cancer can develop when immune surveillance breaks down. Current treatments typically address only one cause of this breakdown. At ArsenalBio we implement cutting edge technologies to deeply understand the biology of human disease and to develop therapies that deliver multiple therapeutic modalities in a single cell.”


    Jane Grogan, PhD

    Chief Scientific Officer

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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