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Senior Scientist, Discovery Immunology

Senior Scientist, Discovery Immunology

WHO WE ARE
Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We seek a talented and experienced Senior Scientist, Discovery Immunology to work onsite based in our  South San Francisco office. 

ArsenalBio’s mission and purpose are very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across multi-scientific disciplines and clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.

This means you’ll have the opportunity to work with the best talent in the field of cell therapy and be part of ONE TEAM, which advances therapies for patients who need it most.

WHAT YOU’LL DO

  • Design, develop, and execute a broad range of cell-based functional and phenotypic in vitro assays to identify mechanisms of T cell activity under a variety of environments
  • Work in teams as the immunology SME to drive the development, execution and interpretation of manual and automated CRISPR screens to identify novel ways to enhance and probe T cells
  • Drive scientific and technical innovation collaboratively with other members of ArsenalBio
  • Summarize and synthesize data across experiments and present findings at all levels of the organization
  • Provide exceptional scientific leadership and mentorship to scientists and research associates
  • Work collaboratively and proactively with colleagues in automation, computational biology, NGS and discovery in a matrixed team structure

  • WHO YOU ARE

  • PhD in Immunology, Cellular Biology, Cancer Biology, or a related field with 2+ years of experience, OR a Master’s degree with 5+ years of experience, OR a Bachelor’s degree with 7+ years of experience. Industry experience is preferred but not required
  • Strong background in immunology with a focus on T cell biology and direct experience with primary immune cell culture; prior experience with genetic engineering of primary immune cells and knowledge of tumor immunology and/or autoimmunity preferred
  • Expertise in successfully developing and executing in vitro cellular assays including immune cell phenotyping, functional assessments, proliferation and cytokine analysis
  • Outstanding written and oral communication skills and the ability to organize and communicate complex data sets clearly and concisely to key stakeholders from diverse backgrounds 
  • Ability to thrive in a fast-paced, collaborative team environment, effectively managing multiple priorities with a proactive mindset, strong self-motivation, and exceptional organizational skills.
  • Preferred Qualifications:
  • Experience with general molecular biology techniques would be preferred
  • Previous experience with pooled/arrayed screening and interpreting scRNAseq and/or screening data would be preferred
  • Experience with tumor or autoimmune disease models would be preferred   

  • BENEFITS AND PAY
    ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge. 

    Our people-first culture cultivates a deep respect for humanity, not only in those we serve but also in one another. We take pride in being part of a company that values and celebrates diversity—in experiences, ideas, and interests. We are empowered in an environment that embraces unity and inclusivity, fostering a sense of belonging and mutual respect.

    We provide powerful tools to empower our employees to take charge of their career paths and reach their full potential. At ArsenalBio, we believe in investing in our employees' well-being—both professionally and personally—because our people are our most valuable asset. Our essential team members bring exceptional expertise in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software, and other fields to turn the possibilities of tomorrow into the realities of today.

    We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and deeply value diversity within our company. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.

    The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $131,200- $160,700. Salary ranges for other locations may vary.  Base pay offered may vary based on job-related knowledge, experience, education, and location. Beyond these considerations, we are committed to pay equity and consider the internal equity of our current employees when making any final offers.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias or to ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    Bold ideas. Reliable data. World-Class Science.

    Designing therapies to cure our most important health challenges requires the audacity to advance a bold idea and explore new biologies with world-class science.

    By pushing at the frontiers of science, challenging what we think we know, and holding ourselves to the highest standards of irrefutable proof, we are reshaping the future of curative cellular therapies.

    Benefits

    ArsenalBio is powered by people.

    And we believe that people work best when given freedom and flexibility in a supportive environment that allows us all to show up as our true selves. We respect that your life extends beyond the work we’ll do here together, and we continually strive to provide you with what you need to care for yourself and your family.

    Health & Wellness

    We offer comprehensive plans that cover medical, dental, vision, and wellness needs, paid at 100% for employees and 80% for eligible dependents. We also encourage and enable our team to enjoy an active lifestyle so we offer standing desks, daily catered lunches, unlimited healthy snacks, and an employer-funded Lifestyle Spending Account that can be used for fitness and wellness expenses. We also provide access to Spring Health, a platform designed to provide easy access to coaching and therapy services to support your mental well-being.

    Financial Well-Being

    We recognize that financial stability fosters peace of mind for our team and their families. We offer a 401(k) employer match, health savings account employer contributions, flexible spending accounts and company-paid life and AD&D insurance in addition to our generous compensation packages. Our team also enjoys free parking, pre-tax commuter benefits for using mass transit and parking, and monthly cell phone reimbursement.

    Time Off

    We want you to enjoy life. We prioritize work-life integration and offer a flexible time off policy, paid holidays and company shutdowns, flexible office hours, a paid leave program, and the permission to manage your time in a way that allows you to meet both your personal and professional responsibilities.

    Mindful Workspace

    Our new offices were thoughtfully designed with the humans of ArsenalBio in mind. With ergonomically-friendly furniture, an open workspace and state-of-the-art lab with inspiring views, collaborative break-out spaces, wellness rooms, micro-kitchens stocked with healthy snacks, and more, our office reflects our holistic commitment to health and happiness.

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.