Discovery

Bold ideas. Reliable data. World-Class Science.

Designing therapies to cure our most important health challenges requires the audacity to advance a bold idea and explore new biologies with world-class science.

By pushing at the frontiers of science, challenging what we think we know, and holding ourselves to the highest standards of irrefutable proof, we are reshaping the future of curative cellular therapies.

Senior Research Associate, In Vivo Translation (2306-U-675-VIVO)

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are looking for a highly motivated Senior Research Associate/Scientist to support the preclinical in vivo pharmacology and translational sciences with the Pre-Clinical Pharmacology group at ArsenalBio. Reporting to a Senior Scientist, the successful candidate will work with teams to design and conduct key in vivo studies and communicate experimental data to support the progress of multiple internal and external collaborative research programs. This role requires an individual with outstanding self-initiative, data analysis, and communication skills.

What You Will Do:

  • Support the preclinical In Vivo Pharmacology team utilizing tumor xenograft models for discovery and IND-enabling studies for CAR-T adoptive cell therapy. Model development to support MOA and TME discovery science as well as pharmacology efforts to advance projects as required.
  • Execute hands-on responsibilities including, but not limited to animal handling and restraint, administration via various routes, in-life measurements, clinical observations, sample collection and processing, and accurate data collection.
  • Collect, analyze, interpret, and present data within the preclinical pharmacology group and across functional areas within our company
  • Design and perform rodent dosing studies, in vivo candidate selection, blood and tissue sampling, flow-cytometry-based PK analysis, surgeries, and isolation of tumor-infiltrating CAR-T cells for MOA as required
  • Support product development and regulatory filings for pivotal clinical studies
  • Oversee studies and/or operations performed at contract research organizations (CROs) as needed

  • What You Will Bring:

  • Bachelors or Masters in oncology, immunology, biotechnology or related field with 4+ years for relevant industry experience.
  • Strong background in tumor biology, immunology and in vivo tumor model development including human xenograft models and development of novel models to solve MOA
  • Extensive hands-on experience with all aspects of running tumor models
  • Experience with various tumor models to demonstrate mechanisms of action, including tumor growth curves, flow-cytometry and RNA endpoints
  • Experience working with immune-oncology antibody or cancer adoptive cell therapy is highly desired
  • Demonstrated ability to work collaboratively in a cross-functional environment
  • Must have excellent troubleshooting, organization, and planning skills, and the ability to work under timeline in a fast-paced environment
  • Excellent written and oral communication skills

  • ArsenalBio prioritizes the providing of a safe and healthy workplace that is consistent with COVID-19 public health guidance and legal requirements.  In order to protect our employees and visitors, we require all visitors (including candidates) and employees to present proof of being fully vaccinated against COVID-19 when coming onsite.

    We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity, and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.


    Ken Drazan, MD
    Founding CEO

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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