Discovery

Bold ideas. Reliable data. World-Class Science.

Designing therapies to cure our most important health challenges requires the audacity to advance a bold idea and explore new biologies with world-class science.

By pushing at the frontiers of science, challenging what we think we know, and holding ourselves to the highest standards of irrefutable proof, we are reshaping the future of curative cellular therapies.

Senior Research Associate/Scientist: IHC and Target Validation

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

ArsenalBio is seeking a Senior Research Associate/ Scientist to drive IHC-based target validation activities as a part of our efforts to develop and commercialize curative immune cell therapies.  This candidate will be primarily responsible for piloting, optimizing, and coordinating large-scale execution of immunohistochemical evaluations of candidate target expression profiles in cell lines, tumor xenografts, and healthy and diseased human tissues

What You Will Do

  • Design and execute cell- and tissue-based monoplex and multiplex immuno- histochemistry to drive development of various cell based immunotherapeutics
  • Perform cell- and tissue-based staining and image analysis to characterize target expression and on-and off-target binding in different organs and tissues, contributing to target validation, safety assessment, and tissue based biomarker identification and validation for clinical use
  • Responsible for method development and qualification/validation, preparation and presentation of scientific findings, and documentation and archiving studies according to regulatory guidelines
  • Responsible for the preparation of standard operating procedures, and overall planning and conduct of IHC activities
  • Summarize and synthesize data across experiments and present findings to colleagues, including diverse management teams
  • Work successfully in matrix organizations via contribution of data, ideas, and presentations
  • What You Will Bring

  • Requirements:
  • Bachelors or Masters in Biology, Biochemistry, Cell Biology, and/or pathology
  • 5+ years of experience in histology laboratory sciences
  • Experience with antigen recall and antibody staining optimization strategies
  • Experience with staining interpretation, expression scoring, and reporting
  • Ability to quickly adapt and learn new skills for changing research priorities
  • Flexible mind with the ability to think outside the box, creative approach to problem-solving.
  • Demonstrated ability to work well in a highly collaborative team environment, coordinate tasks across multiple projects to meet deadlines
  • Willingness to accept other responsibilities outside of initial job description.
  • Strong organizational skills, record keeping and interpersonal communication skills (verbal and written)

  • Preferred skills:
  • Experience with cell-line based immunohistochemistry
  • Experience with human tissue-based immunohistochemistry
  • Experience with multiparamater immunofluorescence (IF) staining, in situ hybridization (ISH), or other emerging technology
  • Experience working in GLP and GCP and CLIA compliant environments and/or experience with GC/LP and CLIA regulatory standards for immunohistochemistry assay development

  • We are committed to hiring the best talent. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.



    Apply     

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.


    Ken Drazan, MD
    Founding CEO

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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