Discovery

Bold ideas. Reliable data. World-Class Science.

Designing therapies to cure our most important health challenges requires the audacity to advance a bold idea and explore new biologies with world-class science.

By pushing at the frontiers of science, challenging what we think we know, and holding ourselves to the highest standards of irrefutable proof, we are reshaping the future of curative cellular therapies.

Scientist, Immunology (2142-N-670-IM)

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. 

Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

ArsenalBio is seeking a talented and driven Scientist to join our Immunology team to develop best-in-class T cell therapies for solid tumors. This candidate will be responsible for design and execution of immunological experiments to enhance the therapeutic activity of reprogrammed T cells.   

What You Will Do:

  • Design and execute immunological/molecular assays to analyze novel genetic perturbations that improve T cell fitness and functionality
  • Analyze and interpret experimental data and summarize key findings to drive critical decision making
  • Coordinate with cross-functional teams for production and functional validation of desired CAR-T products for pipeline advancement
  • Collaborate with Technology Development scientists and engineers to implement functional immune assays at large scale on automated liquid handlers
  • Document experimental design and generation of large scale datasets with attention to detail
  • Present at group meetings and project team meetings

  • What Will You Bring:

  • Ph.D. in Molecular/Cell Biology, Immunology, or related discipline with 0-2 years of industry experience, M.Sc. with 2+ years of industry experience, or B.A./B.S. with 5+ years of industry experience. Leveling will be dependent on experience
  • Hands-on experience with primary immune cell culture, preferably with murine/human T cells
  • Experience performing T cell functional assays (T and tumor cell co-cultures, T cell cytotoxicity assays, etc.) and multicolor flow cytometry (cell surface phenotyping, intracellular cytokine staining, phosphoflow) is strongly preferred
  • Familiarity with one or more of the following is preferred: viral or non-viral T cell editing (e.g. generation of gene KO human T cells via CRISPR/Cas9), standard molecular biology assays (RNA/DNA extraction, etc.), automated liquid handling instrumentation, molecular cloning
  • Excellent organizational, written and verbal communication and interpersonal skills
  • Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results
  • Experience performing data analysis with R/Python, FlowJo, Prism, etc., is a plus. 
  • Ability to multitask as needed in a start-up environment and strong interest in cell therapy and/or immuno-oncology research

  • ArsenalBio prioritizes the providing of a safe and healthy workplace that is consistent with COVID-19 public health guidance and legal requirements.  In order to protect our employees and visitors, we require all visitors (including candidates) and employees to present proof of being fully vaccinated against COVID-19 when coming onsite.

    We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity, and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

    We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

    To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

    Apply     

    ArsenalBio was formed by its investors and scientific founders to discover, develop and commercialize curative and safe cellular therapies for patients with life threatening diseases, initially cancer.

    We believe the most productive and secure route to achieving this goal is to build scaled platforms of technologies challenged with scientific questions to yield informative data from hypothesis driven, well controlled experiments. These data will inform the design of ambitious, best-in-class, lead compositions. Our leads will be rigorously evaluated and honed until we are convinced our matured leads, called development candidates, can be prepared for testing in needy, and vulnerable patients.

    Our products will be designed to speed the transition of cell therapy from hospital-based to outpatient treatments, increasing access to more patients at lower cost to patients, health systems, and insurers.

    To achieve this mission, we are building diverse teams of talented, curious, and caring individuals who believe in our mission and our vision to be sustainable in our business plan, our work habits, and our personal lives.

    Our values create: a foundation for mutual respect, an engaging harmony from many voices, and unselfish behavior to aid our colleagues.

    This is ArsenalBio.
    This is our Company.


    Ken Drazan, MD
    Founding CEO

    Benefits

    Best in Class Health & Wellness Plans

    Flexible Office Hours

    Paid Parental Leave

    Healthy Kitchen Snacks

    Daily Catered Lunches

    Free Onsite Fitness Center

    Unlimited Vacation Days

    Generous compensation and equity packages

    Commuter Benefits

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